反応 #853

反応方程式

2,5-Dimethyl-p-phenylenediamine

benzoylisothiocyanate

→

colorless crystal

収率 98.7%

1,4-di(benzoylthiocarbamoylamino)-2,5-dimethylbenzene

収率 98.7%

溶媒

ethyl acetate

反応条件

後処理

1. 1
   温度After cooling
2. 2
   ろ過the reaction mixture was filtered
3. 3
   洗浄washed with ethyl acetate/n-hexane

実験手順

2,5-Dimethyl-p-phenylenediamine (0.340 g, 2.5 mM) was dissolved in 30 ml of ethyl acetate, and 2 equivalents of benzoylisothiocyanate (0.816 g, 5 mM) were added. The mixture was stirred at room temperature for 10 minutes. After cooling, the reaction mixture was filtered, and washed with ethyl acetate/n-hexane to obtain 1.14 g (98.6% yield) of a colorless crystal of compound A-26.

出典