反応 #84923

反応方程式

tert-butyl 2-(4-bromo-2-oxopyridin-1(2H)-yl)propanoate

2-bromo-5-chlorophenylboronic acid

→

tert-Butyl 2-[4-(2-bromo-5-chlorophenyl)-2-oxopyridin-1(2H)-yl]propanoate

反応条件

実験手順

856 mg (2.75 mmol) of tert-butyl 2-(4-bromo-2-oxopyridin-1(2H)-yl)propanoate (racemate) and 776 mg (3.3 mmol) of 2-bromo-5-chlorophenylboronic acid in the presence of tetrakis(triphenylphosphine)palladium(0) were reacted according to General Method 2A. Yield: 921 mg (80% of theory)

出典