反応 #848

反応方程式

p-hydroxybenzoic acid

decanoic acid chloride

pyridine

→

p-decanoyloxybenzoic acid

溶媒

water

反応条件

後処理

1. 1
   抽出an organic layer was extracted with dichloromethane
2. 2
   洗浄The organic layer was washed with 1N hydrochloric acid
3. 3
   乾燥dried over anhydrous sodium sulfate
4. 4
   workup.DISTILLATIONthe solvent was distilled off
5. 5
   洗浄residue was washed with n-hexane
6. 6
   その他dried
7. 7
   その他to give a crude end product

実験手順

10 Grams of p-hydroxybenzoic acid and 15 g of decanoic acid chloride were stirred at room temperature, and 7.2 g of pyridine was dropwise added. After the mixture was stirred for 1 day, a reaction product was poured into water, and an organic layer was extracted with dichloromethane. The organic layer was washed with 1N hydrochloric acid and dried over anhydrous sodium sulfate, the solvent was distilled off, and then residue was washed with n-hexane and then dried to give a crude end product.

出典