反応 #84455

反応方程式

3,4-difluoronitrobenzene

Et3N

hexan-1-amine

→

title compound

収率 91.0%

2-fluoro-N-hexyl-4-nitroaniline

収率 91.0%

溶媒

EtOAc

反応条件

後処理

1. 1
   温度The reaction mixture was refluxed overnight
2. 2
   濃縮concentrated in vacuo

実験手順

To a solution of 3,4-difluoronitrobenzene (3.18 g, 20 mmol) in EtOAc (50 mL) were added Et3N (2.43 g, 24 mmol) and hexan-1-amine (2.02 g, 20 mmol). The reaction mixture was refluxed overnight, then cooled to rt and concentrated in vacuo to give the title compound as yellow oil (4.37 g, 91%).

出典