反応 #8442

反応方程式

acetic anhydride

triethylamine

dimethylaminopyridine

product

bis-α-naphthyl-(4-[2-hydroxy-ethoxy]-2-hydroxy-phenyl)-triazine

→

bis-αnaphthyl-(4-[2-acetoxy-ethoxy]-2-hydroxy-phenyl)-triazine

溶媒

dichloromethane

反応条件

後処理

1. 1
   温度The reaction mixture is heated to boiling
2. 2
   その他the solvent is removed in vac
3. 3
   洗浄The organic phase is washed with water
4. 4
   乾燥dried with magnesium sulfate
5. 5
   その他After removal of the solvent
6. 6
   その他the residue is chromatographed on silica gel
7. 7
   その他yielding the product

実験手順

9.11 g of acetic anhydride, 18.1 g of triethylamine and 0.73 g of dimethylaminopyridine in 400 ml of anhydrous dichloromethane are added to the product from Example A9. The reaction mixture is heated to boiling. When the reaction is complete (monitoring by TLC), the solvent is removed in vac. and the residue is taken up in dichloromethane. The organic phase is washed with water and dried with magnesium sulfate. After removal of the solvent, the residue is chromatographed on silica gel, yielding the product having the following NMR data:

出典