反応 #84231

反応方程式

N-(4-chloro-2-iodo-5-trifluoromethyl-phenyl)-methanesulfonamide

3-(2,2,2-Trifluoro-ethylsulfanylmethyl)-pent-1yn-3-ol

→

title compound

2-(5-Chloro-1-methanesulfonyl-6-trifluoromethyl-1H-indol-2-yl)-1-(2,2,2-trifluoro-ethylsulfanyl)-butan-2-ol

反応条件

後処理

1. 1
   その他This compound was prepared

実験手順

This compound was prepared using the standard Sonagashira procedure as described in General Procedures Example C, reacting from N-(4-chloro-2-iodo-5-trifluoromethyl-phenyl)-methanesulfonamide (0.60 g, 1.5 mmol) and 3-(2,2,2-Trifluoro-ethylsulfanylmethyl)-pent-1yn-3-ol (0.32 g, 1.5 mmol) to yield the title compound as a yellow sticky oil.

出典