反応 #8397

反応方程式

5-amino-1-(2-phenylethyl)-1H-pyrazole-4-carboxylic acid

urea

→

title compound

収率 105.0%

6-Hydroxy-1-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol

収率 105.0%

溶媒

water

反応条件

後処理

1. 1
   温度cooled
2. 2
   ろ過filtered
3. 3
   洗浄washed with water

実験手順

A mixture of 5-amino-1-(2-phenylethyl)-1H-pyrazole-4-carboxylic acid (1.87 g, 8.1 mmol) and urea (1.46 g, 24 mmol) was heated at 180° C. for 5 h, cooled and the resulting solid suspended in boiling water, filtered and washed with water to give the impure title compound (2.18 g, 105%,) as a cream solid.

出典