反応 #83349

反応方程式

4-(4-nitrophenylthio)quinoline

→

4-(4-aminophenylthio)quinoline

収率 58.3%

溶媒

ethanol

反応条件

後処理

1. 1
   ろ過The solution was filtered through celite
2. 2
   その他the solvent removed

実験手順

4-(4-nitrophenylthio)quinoline (17.0 mmoles, 4.9 g) was dissolved in 200 ml ethanol and hydrogenated over 5 g of 5% Pd/C at 40 psi for 1 hr at room temperature. The solution was filtered through celite and the solvent removed to yield 4-(4-aminophenylthio)quinoline 2.5 g, 58%. Mass spec (FD) 253. Calculated for C15H12N2S: C, 71.40; H, 4.79, N, 11.10. Found: C, 1.12; H, 4.93 N, 10.88.

出典