反応 #83013

反応方程式

3,4,4-trifluoro-3-butenoyl chloride

1-octanethiol

→

desired product

収率 91.3%

3,4,4-trifluoro-3-butenethioic acid, S-octyl ester

収率 91.3%

反応条件

後処理

1. 1
   その他The crude product is purified

実験手順

A mixture of 3,4,4-trifluoro-3-butenoyl chloride (1.7 g, 0.0107 mole) and 1-octanethiol (0.72 g, 0.0049 mole) is heated at 70° C. for 12 h. The crude product is purified by passing through a short column of silica gel to give 1.2 g of the desired product as a pale yellow oil, a 91% yield.

出典