反応 #82862

ord-fa40059e7375469a85c6247e9da4861e

反応方程式

CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)OCC(O)CO)OC(=O)CCCCCCCC=CCCCCCCCC
DOPG
CCCCCCCC/C=C/CCCCCCCCOCCOP(=O)([O-])OCC[N+](C)(C)C
OOPC
→
CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCC/C=C\CCCCCCCC.CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)OCC(O)CO)OC(=O)CCCCCCCC=CCCCCCCCC
DOPG DOPC

反応物

CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)OCC(O)CO)OC(=O)CCCCCCCC=CCCCCCCCC
DOPG
CCCCCCCC/C=C/CCCCCCCCOCCOP(=O)([O-])OCC[N+](C)(C)C
OOPC

試薬

なし

溶媒

ClC(Cl)Cl
chloroform

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他DOPG/DOPC SUV's were prepared
  2. 2
    その他drying off the solvent under a stream of nitrogen gas
  3. 3
    その他was placed under vacuum overnight
  4. 4
    その他to remove traces of solvent
  5. 5
    その他sonicated in a bath type sonicator for 30 minutes until clear,

実験手順

DOPG/DOPC SUV's were prepared by dissolving 40 mg DOPG and 60 mg OOPC in chloroform and drying off the solvent under a stream of nitrogen gas. This dried film was placed under vacuum overnight to remove traces of solvent. The film was then suspended in 2 ml water with vigorous shaking and sonicated in a bath type sonicator for 30 minutes until clear, producing DOPG/DOPC SUV's at a concentration of 50 mg/ml.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05622712uspto-grants-1997_04