反応 #8285

反応方程式

1-benzyloxy-4-phenyl-butan-2-ol

pyridinium chlorochromate

→

title compound

収率 68.3%

1-Benzyloxy-4-phenyl-butan-2-one

収率 68.3%

溶媒

dichloromethane

反応条件

後処理

1. 1
   ろ過The mixture is filtered through a pad of SiO2
2. 2
   濃縮concentrated

実験手順

To a solution of 1-benzyloxy-4-phenyl-butan-2-ol, (8.4 g, 32.8 mmol) in dichloromethane (400 mL) is added a mixture of pyridinium chlorochromate (14.1 g, 65.6 mmol) with SiO2 (14 g) and stirred for 3 h at room temperature. The mixture is filtered through a pad of SiO2 and concentrated to provide the title compound 5.7 g (68%) as a colorless liquid.

出典