反応 #8246

反応方程式

3-(4-(2-methylimidazol-1-yl)-3-fluorophenyl)-5(R)—(N-(t-butoxycarbonyl)isoxazol-3-ylaminomethyl)oxazolidin-2-one

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title product

収率 89.9%

5(S)Isoxazol-3-ylaminomethyl-3-(4-(2-methylimidazol-1-yl)-3-fluorophenyl)oxazolidin-2-one

収率 89.9%

溶媒

dichloromethane

反応条件

実験手順

Using essentially the technique of Example 8, but starting from 3-(4-(2-methylimidazol-1-yl)-3-fluorophenyl)-5(R)—(N-(t-butoxycarbonyl)isoxazol-3-ylaminomethyl)oxazolidin-2-one (510 mg, 1.12 mM), and isolating finally by extraction into dichloromethane gave title product (358 mg).

出典