反応 #82335

反応方程式

N2 (benzyloxycarbonyl)-N1 -isopentyl-L-prolinamide

→

N1 -isopentyl-L-prolinamide

収率 111.5%

溶媒

ethanol

反応条件

後処理

1. 1
   その他The catalyst was removed by filtration
2. 2
   その他the filtrate was evaporated

実験手順

A solution of 5.73 g of N2 -(benzyloxycarbonyl)-N1 -isopentyl-L-prolinamide in 600 ml of ethanol was hydrogenated over 0.8 g of 10% palladium-on-carbon catalyst for 3.75 hours. The catalyst was removed by filtration and the filtrate was evaporated to give 3.4 g of N1 -isopentyl-L-prolinamide as an oil which was used without further purification.

出典