反応 #82230

反応方程式

potassium carbonate

5-bromosalicylaldehyde

N,N-dimethylthiocarbamoyl chloride

→

5-bromo-2-[(N,N-dimethylthiocarbamoyl)oxy]benzaldehyde

収率 78.9%

溶媒

acetone

反応条件

後処理

1. 1
   その他The resulting reaction solution
2. 2
   その他thus precipitated
3. 3
   ろ過were collected by filtration
4. 4
   その他dried

実験手順

8.13 g of 5-bromosalicylaldehyde was dissolved in 100 ml of acetone, followed by the addition of 6.7 g of anhydrous potassium carbonate. With stirring at room temperature, 5.0 g of N,N-dimethylthiocarbamoyl chloride was added to the above solution, and the stirring was continued for two hours. The resulting reaction solution was poured into ice water, and crystals thus precipitated were collected by filtration, and dried to obtain 9.2 g of 5-bromo-2-[(N,N-dimethylthiocarbamoyl)oxy]benzaldehyde.

出典