反応 #82143

反応方程式

N-Allylphenylamine

bromopentane

sodium hydroxide

→

N-allyl-N-pentylphenylamine

収率 56.2%

溶媒

water

反応条件

後処理

1. 1
   抽出extracted with ether (80 ml)
2. 2
   乾燥The extract was dried over potassium carbonate, filterd
3. 3
   濃縮concentrated in vacuum
4. 4
   その他The residue was chromatographed on silica gel

実験手順

N-Allylphenylamine (1.95 g, 14.7 mmol) and bromopentane (2.22 g, 14.7 mmol) were stirred at 80° C. for 16 hours. After cooled to room temperature, the mixture was treated with a solution of sodium hydroxide(714 mg, 17.9 mmol) in water (1.5 ml), stirred for 30 minutes and extracted with ether (80 ml). The extract was dried over potassium carbonate, filterd and concentrated in vacuum. The residue was chromatographed on silica gel to give N-allyl-N-pentylphenylamine (1.68 g) in 56% yield as a colorless oil.

出典