反応 #81389

反応方程式

tetraethyl 2-[3-methoxy-4-hydroxy-1-naphthyl]ethane-1,1-diphosphonate

trimethylsilyl bromide

→

title compound

収率 67.0%

2-[3-Methoxy-4-hydroxy-1-naphthyl]ethane-1,1-diphosphonic Acid

収率 67.0%

反応条件

後処理

1. 1
   その他hydrolysis

実験手順

Following the same method as described in Example 2, 7.12 g (15 mmol) of the tetraethyl 2-[3-methoxy-4-hydroxy-1-naphthyl]ethane-1,1-diphosphonate obtained in Example 11 was treated with trimethylsilyl bromide, and then hydrolysis was effected to obtain 3.64 g of the title compound as pale yellow crystals. The yield was m.p.: 231°-232° C. (dec)

出典