反応 #813301

反応方程式

1-chloro-1,2-dibromotrifluoroethane

1,1,2-trichlorotrifluoroethane

vinylidene chloride

ammonium persulfate sodium formate

→

4-bromo-3-chloro-3,4,4-trifluorobutanoic acid

3,4- dichloro-3,4,4-trifluorobutanoic acid

溶媒

DMF

反応条件

実験手順

A one pot reaction of 1-chloro-1,2-dibromotrifluoroethane (VI) or 1,1,2-trichlorotrifluoroethane (X) with vinylidene chloride in the presence of ammonium persulfate/sodium formate/air in DMF to give 4-bromo-3-chloro-3,4,4-trifluorobutanoic acid (VIII) or 3,4- dichloro-3,4,4-trifluorobutanoic acid (XI).

出典