反応 #810835

反応方程式

1-Acetamino-5-chloronaphthalene

HNO3

NaOH

→

compound 214A

収率 32.0%

1-Amino-5-chloro-4-nitronaphthalene

収率 32.0%

溶媒

AcOH

EtOH

反応条件

実験手順

1-Acetamino-5-chloronaphthalene (150 mg, 0.68 mmol, prepared as described in Example 213A) was dissolved in 1 mL AcOH and treated with 82 μL of red fuming HNO3 and subsequently deacylated with 1 mL 40% aqueous NaOH solution in 3 mL EtOH according to the procedure described in Example 209A to yield 49 mg (32%) of compound 214A as a yellow solid.

出典