反応 #809893

反応方程式

dimethylformamide

3-methyl-2-phenylbutyric acid

oxalyl chloride

→

3-methyl-2-phenylbutyryl chloride

溶媒

methylene chloride

反応条件

後処理

1. 1
   濃縮the mixture was concentrated in vacuo

実験手順

To a stirred solution of 3-methyl-2-phenylbutyric acid (891 mg; 5.0 mmol) and a catalytic amount of dry dimethylformamide (ca. 10 uL) in 10 mL of dry methylene chloride under nitrogen at room temperature was added oxalyl chloride (0.65 mL; 7.5 mmol) dropwise. After 1 hour, the mixture was concentrated in vacuo and used immediately for Step 2.

出典