反応 #807984

反応方程式

methacryloyl chloride

methacrylate

1,1,1-trifluoro-2-trifluoromethyl-2,4-pentanediol

n-butyllithium

→

title compound

1,1,1 -trifluoro-2-trifluoromethyl-2-hydroxy-4-pentyl methacrylate

反応条件

後処理

1. 1
   その他to yield
2. 2
   workup.DISTILLATIONafter distillation at 67° C. at 1.0 mm Hg, 142 g (76%) of the 2° methacrylate as a clear, colorless oil

実験手順

The title compound was prepared in the same fashion as the above described methacrylate using 142 g (0.63 mol) of 1,1,1-trifluoro-2-trifluoromethyl-2,4-pentanediol, 793 mL (1.27 mol) of n-butyllithium (1.6 M in hexane) and 73 g (0.69 mol) of methacryloyl chloride to yield, after distillation at 67° C. at 1.0 mm Hg, 142 g (76%) of the 2° methacrylate as a clear, colorless oil.

出典