反応 #79196

反応方程式

2-amino-N-(2-pyridyl)-4-trifluoromethylaniline

(E)-cinnamoyl chloride

(E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole

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titled compound

(E)-1-(2-Pyridyl)-2-styryl-5-trifluoromethyl-1H-benzimidazole

反応条件

実験手順

The titled compound was prepared from 2-amino-N-(2-pyridyl)-4-trifluoromethylaniline and (E)-cinnamoyl chloride according to the preparation of (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole (Example 1, method A). MW: 365.36; mp: 144.5-145.0° C.; 1H-NMR (CDCl3) δ: 8.82-8.79 (1H, m), 8.12-8.00 (3H, m), 7.57-7.49 (6H, m), 7.41-7.31 (3H, m), 7.11 (1H, d, J=16.1 Hz).

出典