反応 #79175

反応方程式

N-(2-pyridyl)-o-phenylenediamine

(E)-3-methoxycinnamoyl chloride

(E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole

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titled compound

(E)-1-(2-Pyridyl)-2-(4-methoxystyryl)-1H-benzimidazole

反応条件

実験手順

The titled compound was prepared from N-(2-pyridyl)-o-phenylenediamine and (E)-3-methoxycinnamoyl chloride (Wiesler, W. T.; Nakanishi, K. J. Am. Chem. Soc., 1990, 112, 5574) according to the preparation of (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole (Example 1, method A). MW: 327.39; mp: 145.5-146.5° C.; 1H-NMR (CDCl3) δ: 8.81-8.76 (1H, m), 8.04-7.96 (1H, m), 7.98 (1H, d, J=16.1 Hz), 7.85-7.79 (1H, m), 7.56-7.41 (5H, m), 7.37-7.22 (3H, m), 7.00 (1H, d, J=16.1 Hz), 6.88 (1H, d, J=8.4 Hz), 3.83 (3H, s).

出典