反応 #78803

反応方程式

DMF

o-aminothiophenol

Ac2O

→

compound ( A )

収率 32.0%

indole

収率 32.0%

溶媒

benzene

反応条件

後処理

1. 1
   workup.ADDITIONThe reaction mixture was poured
2. 2
   ろ過the precipitated solid was collected by filtration
3. 3
   洗浄The crude solid was washed with MeOH
4. 4
   その他recrystallized from benzene

実験手順

A dry DMF solution of the compound (A-2) (0.01 mole) was added o-aminothiophenol (0.013 mole) and Ac2O (0.5ml) at room temperature. The mixture was stirred at 60° C. for 3 h. The reaction mixture was poured into stirred benzene and the precipitated solid was collected by filtration. The crude solid was washed with MeOH and recrystallized from benzene to afford target compound (A) (32% yield). 1H-NMR spectrum is shown in FIG. 3. Photoluminescence spectrum is shown in FIG. 4.

出典