反応 #78531

反応方程式

N-(4-cyanophenyl)glycine

3-amino-4-methylaminobenzoic acid-N-(2-pyridyl)-N-ethoxycarbonylmethylamide

→

1-Methyl-2-[N-(4-cyanophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-ethoxycarbonylmethylamide

収率 24.0%

溶媒

dichloromethane methanol

反応条件

実験手順

Prepared analogously to Example 25c from N-(4-cyanophenyl)glycine and 3-amino-4-methylaminobenzoic acid-N-(2-pyridyl)-N-ethoxycarbonylmethylamide. Yield: 24% of theory; Rf value: 0.56 (silica gel; dichloromethane/methanol=4:1).

出典