反応 #78005

反応方程式

4-(Bromomethyl)biphenyl

4-phenyltoluene

N-bromosuccinimide

benzoyl peroxide

→

4-(dibromomethyl)biphenyl

溶媒

carbon tetrachloride

反応条件

後処理

1. 1
   温度was refluxed for 24 hours
2. 2
   ろ過filtered

実験手順

4-(Bromomethyl)biphenyl: A mixture of 4-phenyltoluene (4.83 g, 28.7 mmol), N-bromosuccinimide (5.64 g, 31.7 mmol), benzoyl peroxide (catalytic), and anhydrous carbon tetrachloride (35 mL) was refluxed for 24 hours. The mixture was cooled to room temperature and filtered to give a mixture (7.32 g) of 4-(dibromomethyl)biphenyl, 4-(bromomethyl)biphenyl, and 4-phenyltoluene (14:82:4 molar ratio by 1H-NMR). The product was used without further purification in the next step. 1H-NMR of the title compound (300 MHz, CDCl3) δ 7.56-7.60 (m, 4H), 7.33-7.48 (m, 5H), 4.55 (s, 2H). Partial 1H-NMR of 4-(dibromomethyl)biphenyl (300 MHz, CDCl3) δ 6.71 (s, 1H).

出典