反応 #77921

反応方程式

3-cyano-2,4,5-trifluoro-benzoyl fluoride

aluminium chloride

silicon tetrachloride

→

3-Cyano-2,4,5-trifluoro-benzoyl chloride

反応条件

後処理

1. 1
   その他at 65° C.
2. 2
   workup.DISTILLATIONthe mixture was distilled under reduced pressure
3. 3
   その他from 120-122° C.

実験手順

76.6 g of 3-cyano-2,4,5-trifluoro-benzoyl fluoride were initially introduced together with 1 g of anhydrous aluminium chloride at 60-65° C., and 25 g of silicon tetrachloride were then added dropwise at the rate of gas evolution. After the evolution of gas at 65° C. had ceased, the mixture was distilled under reduced pressure. In the boiling range from 120-122° C./14 mbar, 73.2 g of 3-cyano-2,4,5-trifluoro-benzoyl chloride passed over.

出典