反応 #77699

反応方程式

4-methylphenylboronic acid

potassium permanganate

sodium hydroxide

→

4-Carboxyphenylboronic acid

反応条件

後処理

1. 1
   その他at 35-40° C
2. 2
   workup.ADDITIONAfter the addition the reaction
3. 3
   ろ過was filtered
4. 4
   ろ過The product was filtered off
5. 5
   その他A yield of 29.6 g was obtained

実験手順

To a solution of 4-methylphenylboronic acid (34 g, 0.25 mol) in aqueous sodium hydroxide (0.5 N, 1000 mL) was added potassium permanganate (83 g, 0.53 mol) while keeping the temperature at 35-40° C. After the addition the reaction was filtered and the filtrate acidified with concentrated hydrochloric acid (65 mL). The product was filtered off. A yield of 29.6 g was obtained. M.p. 228° C.

出典