反応 #77694

反応方程式

2-Aminobenzonitrile

sodium azide

ammonium chloride

→

pure product

収率 65.2%

5-(2-Aminophenyl)-1-H-tetrazole

収率 65.2%

溶媒

dimethylformamide

反応条件

後処理

1. 1
   その他The solvent was evaporated
2. 2
   その他The crude product was isolated by filtration
3. 3
   その他re-crystallised from water

実験手順

2-Aminobenzonitrile (9.44 g, 80 mmol), sodium azide, (6.24 g, 0.1 mol), ammonium chloride (5.12 g, 0.1 mol) and dimethylformamide (50 mL) were mixed and heated at 120° C. overnight. The solvent was evaporated and the residue taken up in water. The crude product was isolated by filtration and re-crystallised from water. A yield of 8.4 g of pure product was obtained.

出典