反応 #77403

反応方程式

dimethyl-3-nitrobiphenyl-4-malonate

→

3-nitrobiphenyl-4-acetic acid

収率 80.0%

溶媒

hydrochloric acid

反応条件

後処理

1. 1
   ろ過The precipitate was collected by filtration
2. 2
   洗浄washed with water
3. 3
   その他dried

実験手順

Crude dimethyl-3-nitrobiphenyl-4-malonate was heated to reflux in 30 mL of 6N hydrochloric acid for 24 hours. The precipitate was collected by filtration, washed with water and dried to give 4.5 g (80% based on-4-fluoro-3-nitrobiphenyl) of 3-nitrobiphenyl-4-acetic acid as a cream colored solid.

出典