反応 #77370

ord-5d455e72c00943159eb75eeb227bcd48

反応方程式

O=C1Cc2cc(S(=O)(=O)Nc3ccccc3)ccc2N1
2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid phenylamide
O=Cc1cc2cc(OCCN3CCCC3)ccc2[nH]1
5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde
→
O=C1Nc2ccc(S(=O)(=O)Nc3ccccc3)cc2C1=Cc1cc2cc(OCCN3CCCC3)ccc2[nH]1
title compound
O=C1Nc2ccc(S(=O)(=O)Nc3ccccc3)cc2C1=Cc1cc2cc(OCCN3CCCC3)ccc2[nH]1
2-Oxo-3-[5-(2-pyrrolidin-1-yl-ethoxy)-1H-indol-2-ylmethylene]-2,3-dihydro-1H-indole-5-sulfonic acid phenylamide

反応物

O=C1Cc2cc(S(=O)(=O)Nc3ccccc3)ccc2N1
2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid phenylamide
O=Cc1cc2cc(OCCN3CCCC3)ccc2[nH]1
5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid phenylamide was condensed with 5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde to give the title compound.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06706709B2uspto-grants-2004_03