反応 #76908

ord-01aac2af0b064286b5e9411d37ffd66e

反応方程式

COc1ccc(CC2NCCc3cc(OC)c(OC)cc32)cc1OC
1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
COc1ccc(CN)c(OC)c1
2,4-dimethoxybenzylamine
COc1ccc(CNC(=O)CN2CCc3cc(OC)c(OC)cc3C2Cc2ccc(OC)c(OC)c2)c(OC)c1
2-[1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(2,4-dimethoxy-benzyl)-acetamide

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

prepared by reaction of 1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 2,4-dimethoxybenzylamine

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06703392B2uspto-grants-2004_03