反応 #76899

ord-37f55c8c77404704a2a2efd468636a8a

反応方程式

COc1ccc(CC2NCCc3cc(OC)c(OC)cc32)cc1OC
1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
Cc1ccc(CN)cc1
4-methylbenzylamine
COc1ccc(CC2c3cc(OC)c(OC)cc3CCN2CC(=O)NCc2ccc(C)cc2)cc1OC
2-[1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(4-methyl-benzyl)-acetamide

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

prepared by reaction of 1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 4-methylbenzylamine

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06703392B2uspto-grants-2004_03