反応 #76789

反応方程式

(S)-(+)-5′nitrospiro[1-azabicyclo[2.2.2]octane-3,2′(3′H)-furo[2,3-b]pyridine]

→

title compound

収率 92.0%

(S)-(+)-5′-Aminospiro[1-azabicyclo-[2.2.2]octane-3,2′(3′H)-furo[2,3-b]pyridine]

収率 92.0%

溶媒

methanol

反応条件

実験手順

The enantiomer (S)-(+)-5′nitrospiro[1-azabicyclo[2.2.2]octane-3,2′(3′H)-furo[2,3-b]pyridine](6.85 g, 26.2 mmol) treated in the same way as described in example 8A in ammoniated methanol provided the title compound (5.55 g, 24 mmol, 92%): electrospray MS (m/z, relative intensity) 232 ([MH]+, 100).

出典