反応 #76525

ord-54823148799a48c39c1cdf955319cd46

反応方程式

CN1CCc2c(N)cc3[nH]c(=O)c(=O)[nH]c3c2C1
product
CN1CCc2c(N)cc3[nH]c(=O)c(=O)[nH]c3c2C1
6-Amino-1,4,7,8,9,10-hexahydro-9-methyl-pyrido-[3,4-f]quinoxaline-2,3-dione
O=N[O-].[Na+]
sodium nitrite
N#[C][Cu]
CuCN
→
CN1CCc2c(C#N)cc3[nH]c(=O)c(=O)[nH]c3c2C1
title compound
CN1CCc2c(C#N)cc3[nH]c(=O)c(=O)[nH]c3c2C1
1,2,3,4,7,8,9,10-Octahydro-9-methyl-2,3-dioxopyrido[3,4-f]quinoxaline-6-carbonitrile

反応物

CN1CCc2c(N)cc3[nH]c(=O)c(=O)[nH]c3c2C1
product
CN1CCc2c(N)cc3[nH]c(=O)c(=O)[nH]c3c2C1
6-Amino-1,4,7,8,9,10-hexahydro-9-methyl-pyrido-[3,4-f]quinoxaline-2,3-dione
O=N[O-].[Na+]
sodium nitrite
N#[C][Cu]
CuCN

試薬

なし

溶媒

Cl
HCl

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

The product from Example 79 is treated with sodium nitrite in 37% HCl solution at 0° C. The reaction mixture is poured into a solution of CuCN and the title compound is isolated by filtration.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06703391B2uspto-grants-2004_03