反応 #7649

反応方程式

6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one

1,4-dimethylcyclohexanecarbonyl chloride

→

N-[1-(3-Cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]-1,4-dimethylcyclohexanecarboxamide

反応条件

後処理

1. 1
   その他The crude product is used in the next step without further purification

実験手順

In analogy to the procedure for Example 36A, 150 mg (0.67 mmol) 6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one, 130 mg (0.74 mmol) 1,4-dimethylcyclohexanecarbonyl chloride and proportionate amounts of the other reagents are used. The crude product is used in the next step without further purification.

出典