反応 #76484

反応方程式

product

8-Bromo-1,2,3,4-tetrahydro-6-nitro-2-propyl-5-isoquinolinamine

→

title compound

収率 129.7%

1,2,3,4-Tetrahydro-2-propyl-5,6-isoquinolinediamine

収率 129.7%

溶媒

MeOH

反応条件

後処理

1. 1
   その他was hydrogenated at room temperature
2. 2
   濃縮The reaction mixture was concentrated
3. 3
   ろ過collected by filtration

実験手順

A solution of the product from Example 12 (1.50 g, 4.77 mmol) and 20% Pd on carbon (0.30 g) in 75 mL of MeOH was hydrogenated at room temperature and pressure for 24 hours. The reaction mixture was concentrated and the residue was suspended in iPr2O and collected by filtration to give the title compound as a yellow solid (1.27 g, 93%).

出典