反応 #76482

反応方程式

product

8-Bromo-1,2,3,4-tetrahydro-2-methyl-6-nitro-5-isoquinolinamine

→

title compound

収率 90.1%

8-Bromo-1,2,3,4-tetrahydro-2-methyl-5,6-isoquinolinediamine

収率 90.1%

溶媒

THF

反応条件

後処理

1. 1
   ろ過The reaction mixture was filtered
2. 2
   濃縮concentrated

実験手順

A solution of the product from Example 10 (0.78 g, 2.73 mmol) in 100 mL of THF was treated with Raney nickel (1.0 g) and hydrogenated for 1.5 hours at room temperature. The reaction mixture was filtered and concentrated to give the title compound as a tan solid (0.63 g, 90%).

出典