反応 #76183

反応方程式

3-cyano-2,4-dichloro-5-fluoronitrobenzene

hydrogen

→

3-Cyano-2,4-dichloro-5-fluoroaniline

溶媒

ethanol

反応条件

後処理

1. 1
   ろ過The catalyst was filtered off
2. 2
   その他After removing the solvent, 48.0 g of 3-cyano-2,4-dichloro-5-fluoroaniline
3. 3
   その他yield

実験手順

27.0 g of 3-cyano-2,4-dichloro-5-fluoronitrobenzene (0.247 mol), 500 ml of ethanol and 2.18 g of Pd/C were heated to 60° C. and hydrogenated under 3 Mpa of hydrogen pressure for 3 hours. The reaction mixture was cooled to room temperature. The catalyst was filtered off. After removing the solvent, 48.0 g of 3-cyano-2,4-dichloro-5-fluoroaniline were given in 94.7 yield.

出典