反応 #75648

ord-d3e2222c3045443591698a2b7c600b99

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

Compound 15 was prepared by the basic process from 5.0 mmol 3,5-dichloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol styrene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile. Subsequent saponification was carried out using 1.0 ml of sodium hydroxide solution (6N water) in 20.0 ml of ethanol.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06699877B2uspto-grants-2004_03