反応 #75641

反応方程式

4-chloroaniline

ethylglyoxalate

cyclopentadiene

trifluoroacetic acid

→

Compound 3

収率 89.0%

8-chloro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic Acid Ethyl Ester

収率 89.0%

溶媒

acetonitrile

反応条件

実験手順

Compound 3 was prepared in a yield of 89% by the basic process from 5.0 mmol 4-chloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol cyclopentadiene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.

出典