反応 #7551

反応方程式

benzoate

maleic acid

→

benzoate maleate

溶媒

ethyl acetate

反応条件

後処理

1. 1
   workup.ADDITIONwas added
2. 2
   温度after which the resulting mixture was heated
3. 3
   workup.DISSOLUTIONdissolution
4. 4
   温度The reaction mixture was cooled
5. 5
   その他the crystals precipitated
6. 6
   ろ過were collected by filtration

実験手順

In 3 mL of ethyl acetate was dissolved 0.25 g of 1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}-3-azetidinyl=benzoate, and 0.07 g of maleic acid was added thereto, after which the resulting mixture was heated to effect dissolution. The reaction mixture was cooled and the crystals precipitated were collected by filtration to obtain 0.15 g of 1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}-3-azetidinyl=benzoate maleate.

出典