反応 #75411

反応方程式

1-[3-(acetylthio)-2-(methylthiomethyl)propanoyl]-L-proline

→

[3-mercapto-2-(methylthiomethyl)propanoyl]-L-proline

溶媒

water

ammonia

反応条件

後処理

1. 1
   workup.WAITAfter twenty minutes
2. 2
   抽出extracted with ethyl acetate
3. 3
   その他The organic layer is dried
4. 4
   濃縮concentrated to dryness

実験手順

1-[3-(acetylthio)-2-(methylthiomethyl)propanoyl]-L-proline (1.2 g.) is dissolved in a mixture of water (12 ml.) and concentrated ammonia (12 ml.) under a blanket of argon. After twenty minutes, the reaction mixture is acidified and extracted with ethyl acetate. The organic layer is dried and concentrated to dryness to yield 1-([3-mercapto-2-(methylthiomethyl)propanoyl]-L-proline.

出典