反応 #75393

ord-d0f3470974684dfab26c1ed77269735f

反応方程式

CC1(C)N=CC2=C3N=C(Cc4ccccc4)N=C3C(=O)CC2C1=O
7,7-dimethyl-2-benzyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione
Cl.ClCCN1CCOCC1
2-morpholino-ethyl chloride hydrochloride
→
CC1(C)N=CC2=C3N=C(Cc4ccccc4)N=C3C(=O)C(CCN3CCOCC3)C2C1=O.Cl.Cl
7,7-Dimethyl-2-benzyl-5-(2-morpholino-ethyl)-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione dihydrochloride

反応物

CC1(C)N=CC2=C3N=C(Cc4ccccc4)N=C3C(=O)CC2C1=O
7,7-dimethyl-2-benzyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione
Cl.ClCCN1CCOCC1
2-morpholino-ethyl chloride hydrochloride

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

Prepared analogous to Example 23 from 1.6 gm of 7,7-dimethyl-2-benzyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione and 1.2 gm of 2-morpholino-ethyl chloride hydrochloride.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US04176184uspto-grants-1979_11