反応 #75379

反応方程式

HCl

water

p-aminophenol

4-hydroxyphthalic anhydride

→

4-(4'-Hydroxyphthalimido)phenol

溶媒

pyridine

反応条件

後処理

1. 1
   その他In a stirred dry flask under N2
2. 2
   温度the mixture refluxed 5 hr
3. 3
   温度This black solution was cooled
4. 4
   ろ過filtered
5. 5
   洗浄washed
6. 6
   その他dried
7. 7
   その他Recrystallization

実験手順

In a stirred dry flask under N2, to a solution of 54.5 g p-aminophenol (0.5 mole) in 500 ml dry pyridine was added over 10 min at room temperature 82.0 g powdered 4-hydroxyphthalic anhydride (0.31 mole) and the mixture refluxed 5 hr. This black solution was cooled, poured into 1500 ml water, acidified with HCl, filtered, washed, and dried. M.P. 302°-304° C. Recrystallization was unnecessary. Yield 104 g, 82%.

出典