反応 #75371

反応方程式

charcoal

3,5-dichloroaniline

benzaldehyde

p-toluenesulfonic acid monohydrate

→

N-benzylidene-3,5-dichloroaniline

溶媒

toluene

反応条件

後処理

1. 1
   その他To a reaction flask, equipped with a Dean-Stark trap
2. 2
   温度The reaction mixture is then warmed
3. 3
   温度to reflux
4. 4
   その他the water (1.65 ml.) collected
5. 5
   その他by azeotroping
6. 6
   その他The cooled reaction mixture
7. 7
   その他to give an amber oil that
8. 8
   その他crystallizes

実験手順

To a reaction flask, equipped with a Dean-Stark trap, is added 3,5-dichloroaniline (16.2 g., 0.10 mole), benzaldehyde (10.6 g., 0.10 mole), p-toluenesulfonic acid monohydrate (0.2 g.), and toluene (100 ml.). The reaction mixture is then warmed to reflux and the water (1.65 ml.) collected by azeotroping. The cooled reaction mixture is treated with charcoal and the filtrate reduced in vacuo to give an amber oil that crystallizes on standing to give N-benzylidene-3,5-dichloroaniline which is recrystallized from pentane. m.p. 52°-53° C.

出典