反応 #75353

ord-d59da3bc0c2c42b883b835031853d03e

反応方程式

COc1cc2c(cc1OC)C(=CO)C(=O)N2
5,6-Dimethoxy-3-hydroxymethylene oxindole
COc1ccc(CCN)cc1OC
2(3,4-dimethoxyphenyl)ethylamine
CC(=O)O
acetic acid
COc1ccc(CCNC=C2C(=O)Nc3cc(OC)c(OC)cc32)cc1OC
5,6-Dimethoxy-3[2(3,4-dimethoxyphenyl)ethylamino methylene]oxindole

溶媒

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他to give 6.30 g

実験手順

5.00 g. of 5,6-Dimethoxy-3-hydroxymethylene oxindole, 6.00 g. of 2(3,4-dimethoxyphenyl)ethylamine and 2.20 acetic acid in 40 ml. benzene was reacted as described in Example 5 to give 6.30 g. product, m.p. 164°-166° C.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US04176191uspto-grants-1979_11