反応 #75209

ord-9a84703462a74bf1afd0b33f20befa25

反応方程式

CC(=O)SCC(CCC(O)C(C)C)C(=O)N1CCC[C@H]1C(=O)O
1-[2-(acetylthiomethyl)-5-hydroxy-6-methylheptanoyl]-L-proline
CSCC(CSC(C)=O)C(=O)N1CCC[C@H]1C(=O)O
1-[3-acetylthio-2-(methylthiomethyl)propanoyl]-L-proline
→
CC(C)C(O)CCC(CS)C(=O)N1CCC[C@H]1C(=O)O
1-[2-mercaptomethyl-5-hydroxy-6-methylheptanoyl]-L-proline

反応物

CC(=O)SCC(CCC(O)C(C)C)C(=O)N1CCC[C@H]1C(=O)O
1-[2-(acetylthiomethyl)-5-hydroxy-6-methylheptanoyl]-L-proline
CSCC(CSC(C)=O)C(=O)N1CCC[C@H]1C(=O)O
1-[3-acetylthio-2-(methylthiomethyl)propanoyl]-L-proline

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

By substituting 1-[2-(acetylthiomethyl)-5-hydroxy-6-methylheptanoyl]-L-proline for the 1-[3-acetylthio-2-(methylthiomethyl)propanoyl]-L-proline in the procedure of Example 17, 1-[2-mercaptomethyl-5-hydroxy-6-methylheptanoyl]-L-proline is obtained.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US04175199uspto-grants-1979_11