反応 #75207

ord-1b7f77d46b8142d7931be0ae959e1bf3

反応方程式

CC(=O)SCC(CCC(=O)C(C)C)C(=O)O
2-acetylthiomethyl-5-oxo-6-methylheptanoic acid
CC(=O)CC(CSC(C)=O)C(O)=S
2-(acetylthiomethyl)-3-acetylthiopropanoic acid
CC(C)(C)OC(=O)[C@@H]1CCCN1
L-proline tert.butyl ester
→
CC(=O)SCC(CCC(=O)C(C)C)C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C
(2-(Acetylthiomethyl)-5-oxo-6-methylheptanoyl]-L-proline tert.butyl ester

反応物

CC(=O)SCC(CCC(=O)C(C)C)C(=O)O
2-acetylthiomethyl-5-oxo-6-methylheptanoic acid
CC(=O)CC(CSC(C)=O)C(O)=S
2-(acetylthiomethyl)-3-acetylthiopropanoic acid
CC(C)(C)OC(=O)[C@@H]1CCCN1
L-proline tert.butyl ester

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他is obtained

実験手順

By substituting 2-acetylthiomethyl-5-oxo-6-methylheptanoic acid for the 2-(acetylthiomethyl)-3-acetylthiopropanoic acid in the procedure of Example 2, 1-[2-acetylthiomethyl)-5-oxo-6-methylheptanoyl]-L-proline tert.butyl ester is obtained.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US04175199uspto-grants-1979_11