反応 #75034

反応方程式

2-butylamino-4-methyloxazole

hexyl isocyanate

→

product

1-Butyl-3-hexyl-1-(4-methyl-2-oxazolyl)urea

溶媒

benzene

反応条件

後処理

1. 1
   温度under reflux for 3 hours
2. 2
   その他The solution was evaporated
3. 3
   workup.DISSOLUTIONthe residual oil dissolved in ether
4. 4
   洗浄washed with dilute HCl
5. 5
   その他dried
6. 6
   その他re-evaporated
7. 7
   workup.DISSOLUTIONThe residue was dissolved in petroleum spirit (40°-60° C.) carbon
8. 8
   workup.ADDITIONtreated
9. 9
   その他re-evaporated under vacuum

実験手順

A solution of 2-butylamino-4-methyloxazole (10.0 g, 0.065 mol) and hexyl isocyanate (8.25 g, 0.065 mol) in dry benzene was heated under reflux for 3 hours. The solution was evaporated and the residual oil dissolved in ether, washed with dilute HCl, dried and re-evaporated. The residue was dissolved in petroleum spirit (40°-60° C.) carbon treated and re-evaporated under vacuum to give the pure product as a pale oil.

出典