反応 #74953

反応方程式

chloromethyl pivalate

N-(2-chloro-benzyl)-2-(2-thienyl)ethylamine

→

title compound

収率 51.0%

5-(2-chloro-benzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride

収率 51.0%

溶媒

dimethylsulfoxide

反応条件

実験手順

66.5 g (0.44 M) chloromethyl pivalate is reacted by heating, for 3 hours, with a solution of 103 g (0.4 M) N-(2-chloro-benzyl)-2-(2-thienyl)ethylamine in 300 ml dimethylsulfoxide, to give the title compound in a yield of 51%.

出典